Open up the program. highlite the drive you want to search. A box will pop up saying "No valid support file system present on volume. Would you like to scan drive"
Select yes. A new window opens, click the scroll button on file system and uncheck the two that dont apply usually FAT and Ext3fs. Keep NTFS checked if thats right, then scan the drive.
I haven't used it in a very long time, but I think it will ask you for the first letter of the file that you select to recover. Any letter or number will work to recover the file.
Notice also, there is a help file and its pretty all inclusive.
Another thing also, I don't think that it is considered a lost file until you empty the recycle bin